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CasNo: 65666-07-1
MF: C25H22O10
Appearance: powder
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Silymarin is a kind of flavonoid complex consisting of silybin, silydianin, and silychrisin, derived from the milk thistle plant. It is a kind of potent antioxidant, anti-cancer agent as well as liver protecting agent. It has a lot of pharmaceutical functions. For example: (1) Promotes healthy liver function and general health; (2) Strengthen the normal cellular defense system to protect the liver tissue; (3) Help to eliminate the toxin accumulating in the liver; (4) Increase the survival rate of patients of cirrhosis; (5) Protect our body against industrial poisons; (6) Antidote against the death cap mushroom. Silymarin exerts its pharmaceutical effects through various mechanism including scavenging free radicals, increasing glutathione (has detoxifying effect) level in the liver, increasing the levels of antioxidant enzymes such as superoxide dismutase, stimulating liver protein synthesis and inhibiting the synthesis of leukotrienes.
Milk thistle (Silybum [Carduus] marianus) is a spiny European plant with white-veined leaves and milky sap, the seed of which is used to treat liver disease.Milk thistle seed extract is used orally in the treatment of alcoholic and other cirrhoses and in Europe intravenously for its hepatoprotective effect in Amanita and other mushroom poisonings. It is grown in this country primarily as a “liver cleanser” and is reputed to protect this organ from a wide array of toxins.Milk thistle seed contains the active principle silymarin, a complex of flavonolignan compounds including silibinin (silybin), silidianin, and silychristin.
Silymarin has been used to study:its in vitro antiviral, antibacterial, antifungal activities and cytotoxicityits effect of silymarin on bladder contractions in cyclophosphamide (CYP)-induced cystitis rat model its effect on liver toxication induced by Fumonisin B1 in mice
The CAS number of Silymarin is 65666-07-1.
More information of Silymarin 65666-07-1 are:
CAS Number |
65666-07-1 |
Density |
1.527 g/cm3 |
Melting Point |
158 °C |
Boiling Point |
793 °C at 760 mmHg |
Flash Point |
274.4 °C |
Vapor Pressure |
1.63E-26mmHg at 25°C |
Refractive Index |
1.684 |
HS CODE |
3003909090 |
PSA |
155.14000 |
LogP |
2.36270 |
The chemical formula of Silymarin is C25H22O10 which containing 25 Carbon atoms,22 Hydrogen atoms and 10 Oxygen atoms,and the molecular weight, and the molecular weight of Silymarin is 482.4362
Silymarin is a kind of flavonoid complex consisting of silybin, silydianin, and silychrisin, derived from the milk thistle plant. It is a kind of potent antioxidant, anti-cancer agent as well as liver protecting agent. It has a lot of pharmaceutical functions. For example: (1) Promotes healthy liver function and general health; (2) Strengthen the normal cellular defense system to protect the liver tissue; (3) Help to eliminate the toxin accumulating in the liver; (4) Increase the survival rate of patients of cirrhosis; (5) Protect our body against industrial poisons; (6) Antidote against the death cap mushroom. Silymarin exerts its pharmaceutical effects through various mechanism including scavenging free radicals, increasing glutathione (has detoxifying effect) level in the liver, increasing the levels of antioxidant enzymes such as superoxide dismutase, stimulating liver protein synthesis and inhibiting the synthesis of leukotrienes.
InChI:InChI=1/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1
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