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CasNo： 39537-23-0
MF： C8H15N3O4
Quality products make an important contribution to long-term revenue and profitability. Bulk supply high purity L-Alanyl-L-Gluatamine 39537-23-0, Paid sample available
This supplement provides a stable form of L-glutamine while in solution.
N-(α-chloro)propionyl-L-glutamine
alanylglutamine
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide;
In
water;
at 60 ℃;
under 1500.15 Torr;
|
L-glutamine
N-Cbz-Ala
alanylglutamine
| Conditions | Yield |
|---|---|
|
N-Cbz-Ala;
With
hexachloroethane; triphenylphosphine;
In
tetrahydrofuran;
at 0 ℃;
for 1.5h;
L-glutamine;
With
potassium hydroxide;
In
tetrahydrofuran; dichloromethane; water;
at 0 ℃;
for 2h;
pH=13;
With
sulfuric acid; hydrogen;
more than 3 stages;
Product distribution / selectivity;
|
65% |
|
N-Cbz-Ala;
With
hexachloroethane; triphenylphosphine;
In
toluene;
at 0 ℃;
for 3h;
L-glutamine;
With
sodium hydroxide;
In
water; toluene;
at 15 ℃;
for 1.5h;
pH=12;
With
hydrogenchloride; hydrogen;
more than 3 stages;
Product distribution / selectivity;
|
48% |
|
N-Cbz-Ala;
With
hexachloroethane; triphenylphosphine;
In
acetonitrile;
at 5 ℃;
for 1h;
L-glutamine;
With
sodium hydroxide; potassium carbonate;
In
water; acetonitrile;
at 5 ℃;
for 2h;
pH=10;
With
hydrogenchloride; trifluoroacetic acid;
more than 3 stages;
Product distribution / selectivity;
|
45% |
The CAS number of L-Alanyl-L-Glutamine is 39537-23-0.
More information of L-Alanyl-L-Glutamine 39537-23-0 are:
|
CAS Number |
39537-23-0 |
|
Density |
1.305g/cm3 |
|
Melting Point |
215 °C |
|
Boiling Point |
615.4 °C at 760 mmHg |
|
Flash Point |
326 °C |
|
Vapor Pressure |
1E-16mmHg at 25°C |
|
Refractive Index |
10 ° (C=5, H2O) |
|
HS CODE |
29241990 |
|
PSA |
135.51000 |
|
LogP |
-0.04000 |
|
Pka |
3.12±0.10(Predicted) |
Synonyms for L-Alanyl-L-Glutamine 39537-23-0:Glutamine,N2-L-alanyl- (7CI);L-Glutamine, N2-L-alanyl-;Dipeptamin;Dipeptiven;GlutaMAX;L-Ala-L-Gln;L-Alanyl-L-glutamine;Glutamax I;
The chemical formula of L-Alanyl-L-Glutamine is C8H15N3O4 which containing 8 Carbon atoms,15 Hydrogen atoms,3 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of L-Alanyl-L-Glutamine is 217.225.
L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.
InChI:InChI=1/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)
Relevant articles related to L-Alanyl-L-Glutamine:
|
Article |
Source |
|
Gene cloning and characterization of α-amino acid ester acyl transferase in empedobacter brevis ATCC14234 and Sphingobacterium siyangensis AJ2458 |
Abe, Isao,Hara, Seiichi,Yokozeki, Kenzo experimental part, p. 2087 - 2092 (2012/02/14) |
|
Recovery of ammonia in the dipeptide manufacturing processes |
Kato, Satoshi,Sano, Takahiro,Sugaya, Toru , p. 132 - 135 (2013/09/07) |
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