Question 1

What is the BETA-HYDROXYISOVALERIC ACID?

Accepted Answer

BETA-HYDROXYISOVALERIC ACID is colorless to light yellow liquid, while it's Molecular Formula is C5H10O3. colorless to light yellow liquid 3-Hydroxy-3-methylbutyric acid is a useful biochemical for synthesis and proteomics research. It is used as an indicator of biotin deficiency. Further, it is used to increase muscle mass and decrease muscle breakdown. In addition to this, it is involved in the protein synthesis.

Question 2

What is the CAS number for BETA-HYDROXYISOVALERIC ACID?

Accepted Answer

The CAS number of BETA-HYDROXYISOVALERIC ACID is 625-08-1.

Question 3

What is BETA-HYDROXYISOVALERIC ACID (625-08-1) used for?

Accepted Answer

β-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β- methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. It plays a part in protein synthesis and was discovered by Dr. Steven L. Nissen at Iowa State University. It has been used in scientific studies to purportedly increase muscle mass and decrease muscle breakdown. Nissen held the original patent on the metabolite as a nutritional supplement. It was discovered in pigs, and small quantities can also be found in grapefruit, alfalfa, and catfish. As a supplement it is usually sold as a calcium salt. Research published in the Journal of Applied Physiology has shown that HMB may have an effect on increasing muscle weight and strength. A review in Nutrition & Metabolism provides an in depth and objective analysis of HMB research. The same study lists as HMB' s proposed mechanisms of action the following: Increased sarcolemmal integrity via conversion to HMG-CoA Enhanced protein synthesis via the mTOR pathway Depression of protein degradation through inhibition of the ubiquitin pathway Three grams of Calcium beta-hydroxy-beta-methylbutyrate per day may help muscles combat protein breakdown, assist in muscle repair and support increased endurance. Studies suggest its benefits may be greater for the untrained. Also, well-controlled scientific studies have found increases in muscle mass and decreases in body fat in 70 year old men. It has helped patients with chronic obstructive pulmonary disease in hospital intensive care units, muscle wasting associated with HIV or AIDS and with cancer, and trauma victims with severe injuries. The human body produces about 0.2 - 0.4 grams per day. Standard doses in research studies have been 1.5 to 3.0 grams per day, usually divided into two doses.InChI:InChI=1/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7)

Conditions	Yield
With water; sodium hydroxide; at 20 ℃;	93%
With sodium hydroxide; In water; at 20 ℃;	93%

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HMB ACID LIQUID

Basic information

Physical and Chemical Properties

Product Details

High quality purity >99% HMB ACID LIQUID 625-08-1 for sale

BETA-HYDROXYISOVALERIC ACID(Cas 625-08-1) Usage

625-08-1 Relevant articles

Method for producing aliphatic carboxylic acid compound and pyridine compound adduct of aliphatic ketone compound

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, (2020/05/02)

Preparation method of calcium [beta]-hydroxy-[beta]-methylbutyrate

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, (2020/07/24)

PROCESS FOR PREPARING 3-HYDROXY-3-METHYLBUTYRATE (HMB) AND SALTS THEREOF

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Page/Page column 8-9, (2020/10/31)

SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE

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Paragraph 000642, (2019/06/05)

625-08-1 Process route

625-08-1 Upstream products

625-08-1 Downstream products

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