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CasNo: 39537-23-0
MF: C8H15N3O4
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L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.
This supplement provides a stable form of L-glutamine while in solution.
The CAS number of L-Alanyl-L-Glutamine is 39537-23-0.
More information of L-Alanyl-L-Glutamine 39537-23-0 are:
CAS Number |
39537-23-0 |
Density |
1.305g/cm3 |
Melting Point |
215 °C |
Boiling Point |
615.4 °C at 760 mmHg |
Flash Point |
326 °C |
Vapor Pressure |
1E-16mmHg at 25°C |
Refractive Index |
10 ° (C=5, H2O) |
HS CODE |
29241990 |
PSA |
135.51000 |
LogP |
-0.04000 |
Pka |
3.12±0.10(Predicted) |
The chemical formula of L-Alanyl-L-Glutamine is C8H15N3O4 which containing 8 Carbon atoms,15 Hydrogen atoms,3 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight, and the molecular weight of L-Alanyl-L-Glutamine is 217.225
L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.
InChI:InChI=1/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)
Relevant articles related to L-Alanyl-L-Glutamine:
Article |
Source |
ALANYL GLUTAMINE COMPOUND AND PREPARATION METHOD THEREOF |
- Paragraph 0096, (2015/02/19) |
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