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CasNo: 625-08-1
MF: C5H10O3
Appearance: colorless to light yellow liquid
High quality purity >99% HMB ACID LIQUID 625-08-1 for sale We supply high quality BETA-HYDROXYISOVALERIC ACID (CAS 625-08-1), in stock, factory directly supply to clients, lower prices, more competitiveness.
BETA-HYDROXYISOVALERIC ACID is colorless to light yellow liquid, while it's Molecular Formula is C5H10O3. 3-Hydroxy-3-methylbutyric acid is a useful biochemical for synthesis and proteomics research. It is used as an indicator of biotin deficiency. Further, it is used to increase muscle mass and decrease muscle breakdown. In addition to this, it is involved in the protein synthesis.
The CAS number of BETA-HYDROXYISOVALERIC ACID is 625-08-1.
More information of BETA-HYDROXYISOVALERIC ACID 625-08-1 are:
Synonyms |
b-Hydroxyisovaleric acid;b-Hydroxy-b-methylbutyric acid;3-Hydroxy-3-methylbutyric acid;3-Hydroxyisovaleric acid;3-Hydroxy-3-methylbutanoic acid;Butyricacid, 3-hydroxy-3-methyl- (6CI,7CI,8CI); |
CAS Number |
625-08-1 |
Molecular Formula |
C5H10O3 |
Molecular Weight |
118.133 |
Density |
1.144 g/cm3 |
Melting Point |
-80 °C(lit.) |
Boiling Point |
242.8 °C at 760 mmHg |
Flash Point |
114.9 °C |
HS CODE |
29181990 |
PSA |
57.53000 |
LogP |
0.23200 |
Pka |
4.38±0.10(Predicted) |
β-Hydroxy β-methylbutyric acid (HMB), or β-hydroxy β- methylbutyrate, is a metabolite of the essential amino acid leucine and is synthesized in the human body. It plays a part in protein synthesis and was discovered by Dr. Steven L. Nissen at Iowa State University. It has been used in scientific studies to purportedly increase muscle mass and decrease muscle breakdown. Nissen held the original patent on the metabolite as a nutritional supplement. It was discovered in pigs, and small quantities can also be found in grapefruit, alfalfa, and catfish. As a supplement it is usually sold as a calcium salt. Research published in the Journal of Applied Physiology has shown that HMB may have an effect on increasing muscle weight and strength. A review in Nutrition & Metabolism provides an in depth and objective analysis of HMB research. The same study lists as HMB' s proposed mechanisms of action the following: Increased sarcolemmal integrity via conversion to HMG-CoA Enhanced protein synthesis via the mTOR pathway Depression of protein degradation through inhibition of the ubiquitin pathway Three grams of Calcium beta-hydroxy-beta-methylbutyrate per day may help muscles combat protein breakdown, assist in muscle repair and support increased endurance. Studies suggest its benefits may be greater for the untrained. Also, well-controlled scientific studies have found increases in muscle mass and decreases in body fat in 70 year old men. It has helped patients with chronic obstructive pulmonary disease in hospital intensive care units, muscle wasting associated with HIV or AIDS and with cancer, and trauma victims with severe injuries. The human body produces about 0.2 - 0.4 grams per day. Standard doses in research studies have been 1.5 to 3.0 grams per day, usually divided into two doses.
InChI:InChI=1/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7)
Articles related to BETA-HYDROXYISOVALERIC ACID:
Article |
Source |
Method for producing aliphatic carboxylic acid compound and pyridine compound adduct of aliphatic ketone compound |
- , (2020/05/02) |
Preparation method of calcium [beta]-hydroxy-[beta]-methylbutyrate |
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