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CasNo: 372-75-8
MF: C6H13N3O3
Appearance: white powder
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An essential intermediate in the biosynthesis of nitric oxide.
L-citrulline copper complex
Citrulline
Conditions | Yield |
---|---|
With
sodium sulfide;
In
water;
Reagent/catalyst;
Large scale;
|
L-arginine
Citrulline
Conditions | Yield |
---|---|
for 46 - 120h;
Product distribution / selectivity;
Enzymatic reaction;
|
91% |
With
dihydrogen peroxide;
K[Ru(Hedta)Cl]*2H2O;
|
71% |
durch Einwirkung von Faeulnisbakterien;
|
|
durch Einwirkung von Pseudomonas aeruginosa (Bacillus pyocyaneus);
|
|
durch Einwirkung von Streptococcus faecalis;
|
|
With
recombinant neuronal nitric oxide synthase;
Further Variations:;
Reagents;
Enzyme kinetics;
|
|
With
arginine deiminase; potassium 2-(N-morpholino)ethanesulfonate; magnesium chloride;
at 25 ℃;
pH=5.6;
Enzyme kinetics;
|
|
With
neuronal nitric oxide synthase μ; NADPH; calmodulin;
at 25 ℃;
Further Variations:;
Reaction partners;
Reagents;
pH-values;
Enzyme kinetics;
|
|
With
magnesium chloride;
In
various solvent(s);
at 25 ℃;
pH=5.6;
Enzyme kinetics;
|
|
With
glutamate dehydrogenase; 1,4-dihydronicotinamide adenine dinucleotide;
In
various solvent(s);
at 25 ℃;
pH=7.0;
Enzyme kinetics;
|
|
With
magnesium chloride;
In
various solvent(s);
at 25 ℃;
pH=5.6;
Enzyme kinetics;
|
|
With
magnesium chloride;
In
various solvent(s);
at 25 ℃;
pH=7.5;
Enzyme kinetics;
|
|
With
magnesium chloride;
In
various solvent(s);
at 25 ℃;
pH=6.0;
Enzyme kinetics;
|
|
With
full-length inducible nitric oxide synthase; (6R)-5,6,7,8-tetrahydro-L-biopterin; oxygen;
at 37 ℃;
pH=7.4;
Kinetics;
aq. buffer;
|
|
With
1,4-dithio-D,L-threitol; human neuronal nitric oxide synthase; NADPH; calcium chloride; hemoglobin; calmodulin; (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin;
at 20 ℃;
pH=7.4;
Concentration;
Reagent/catalyst;
Kinetics;
aq. Hepes buffer;
Enzymatic reaction;
|
|
With
α-ketoglutaric acid; bovine liver glutamate dehydrogenase type II; recombinant Giardia lamblia arginine deiminase; water;
at 25 ℃;
pH=7.5;
pH-value;
Reagent/catalyst;
Time;
Kinetics;
aq. buffer;
|
|
With
arginine deiminase K5T/D44E/H404R mutant;
at 37 ℃;
Reagent/catalyst;
pH-value;
Kinetics;
aq. phosphate buffer;
|
|
With
1,4-dithio-D,L-threitol; neuronal NO synthase; NADPH; FAD; 4-(2-hydroxyethyl)-1-piperazinepropanesulfonic acid; (6-R,S)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride; Flavin mononucleotide; superoxide dismutase; catalase; calmodulin;
at 25 ℃;
Enzymatic reaction;
|
|
With
hydrogenchloride; water;
at 38 ℃;
for 96h;
pH=6;
|
The CAS number of L(+)-Citrulline is 372-75-8.
More information of L(+)-Citrulline 372-75-8 are:
CAS Number |
372-75-8 |
Density |
1.289 g/cm3 |
Melting Point |
214 °C |
Boiling Point |
386.7 °C at 760 mmHg |
Flash Point |
187.7 °C |
Vapor Pressure |
4.7E-07mmHg at 25°C |
Refractive Index |
26 ° (C=8, 6mol/L HCl) |
HS CODE |
29241900 |
PSA |
118.44000 |
LogP |
0.63830 |
Pka |
2.43(at 25℃) |
Synonyms for L(+)-Citrulline 372-75-8:L-Citrullin;L-Cit-OH;L-Citrulline;N5-(Aminocarbonyl)ornithine;L-Citrulline (Fermentation);H-Cit-OH;.delta.-Ureidonorvaline;2-Amino-5-uredovaleric acid;Ngamma-carbamylornithine;delta-Ureidonorvaline;N~5~-(aminocarbonyl)ornithine;2-amino-5-(carbamoylamino)pentanoic acid;L-Citrulline;(2S)-2-amino-5-(carbamoylamino)pentanoic acid;Ornithine, N5-carbamoyl-, L- (8CI);L-Ornithine, N5-(aminocarbonyl)-;Ornithine, N5-(aminocarbonyl)-;Citrulline, L-;Ornithine, N5-carbamoyl-, L-;Citrulline;L-Ornithine,N5-(aminocarbonyl)-;.alpha.-Amino-.delta.-ureidovaleric acid;N5-(Aminocarbonyl)-L-ornithine;alpha-Amino-delta-ureidovaleric acid;N(.delta.)-Carbamylornithine;
The chemical formula of L(+)-Citrulline is C6H13N3O3 which containing 6 Carbon atoms,13 Hydrogen atoms,3 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of L(+)-Citrulline is 175.188.
L(+)-Citrulline, an amino acid, is a white powder that serves as an essential intermediate in the biosynthesis of nitric oxide from L-arginine. It plays a crucial role in various physiological processes and has been found to have potential applications in the pharmaceutical, nutritional, and biochemical industries.
InChI:InChI=1/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
Relevant articles related to L(+)-Citrulline:
Article |
Source |
Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase |
Tejero, Jesus,Biswas, Ashis,Haque, Mohammad Mahfuzul,Wang, Zhi-Qiang,Hemann, Craig,Varnado, Cornelius L.,Novince, Zachary,Hille, Russ,Goodwin, Douglas C.,Stuehr, Dennis J. , p. 163 - 174 (2011) |
Arginine Deiminase Uses an Active-Site Cysteine in Nucleophilic Catalysis of L-Arginine Hydrolysis |
Lu, Xuefeng,Galkin, Andrey,Herzberg, Osnat,Dunaway-Mariano, Debra , p. 5374 - 5375 (2004) |
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