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CasNo： 334-50-9
MF： C7H19 N3 . 3 Cl H
Appearance： white crystalline powder
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Spermidine Trihydrochloride is a NOS1 inhibitor and NMDA and T4 activator. Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. It was in a structural and functional study of polyamines, where potassium and sodium ions were found to promote different effects when binding with polyamines. Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.
N-(3-azidopropyl)-1,4-diaminobutane
spermidine trihydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
ethanol;
for 18h;
under 3102.9 Torr;
Ambient temperature;
|
91% |
![tert-butyl {4-{[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]amino}butyl}carbamate](/upload/2025/6/2caf06f4-3807-492c-be45-8dde96ec721c.png)
tert-butyl {4-{[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]amino}butyl}carbamate
spermidine trihydrochloride
| Conditions | Yield |
|---|---|
|
tert-butyl {4-{[3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)propyl]amino}butyl}carbamate;
With
hydrazine hydrate;
In
ethanol;
for 4h;
Reflux;
Large scale;
With
hydrogenchloride;
In
ethanol; water;
Reagent/catalyst;
Reflux;
Large scale;
|
78.9% |
The CAS number of SPERMIDINE TRIHYDROCHLORIDE is 334-50-9.
More information of SPERMIDINE TRIHYDROCHLORIDE 334-50-9 are:
|
CAS Number |
334-50-9 |
|
Density |
0.906 g/cm3 |
|
Melting Point |
257-259 °C(lit.) |
|
Boiling Point |
246.6 °C at 760 mmHg |
|
Flash Point |
118.1 °C |
|
Vapor Pressure |
0.0269mmHg at 25°C |
|
HS CODE |
29212900 |
|
PSA |
64.07000 |
|
LogP |
3.86120 |
Synonyms for SPERMIDINE TRIHYDROCHLORIDE 334-50-9:1,4-Butanediamine,N-(3-aminopropyl)-, trihydrochloride (8CI,9CI); Spermidine hydrochloride; Spermidinetrihydrochloride
The chemical formula of SPERMIDINE TRIHYDROCHLORIDE is C7H19 N3 . 3 Cl H which containing 7 Carbon atoms,20 Hydrogen atoms,1 Nitrogen atoms and 1 Chlorine atoms,and the molecular weight of SPERMIDINE TRIHYDROCHLORIDE is 254.631.
Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins. Additionally, spermidine stimulates T4 polynucleotide kinase activity. It is involved in growth, development, and the stress response in plants.
InChI:InChI=1/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
Relevant articles related to SPERMIDINE TRIHYDROCHLORIDE:
|
Article |
Source |
|
Synthesis process of spermidine and intermediate thereof |
- Paragraph 0047-0053, (2021/10/27) |
|
Synthesis of 13C-dilabeled 4-coumaroylspermidines |
Geneste, Herve,Hesse, Manfred , p. 15199 - 15214 (2007/10/03) |
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