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CasNo: 5080-50-2
MF: C9H17NO4.HCl
Appearance: Crystallline powder
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Crystallline powder
Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund''s adjuvant.
The CAS number of O-Acetyl-L-carnitine hydrochloride is 5080-50-2.
Synonyms for O-Acetyl-L-carnitine hydrochloride 5080-50-2:1-Propanaminium,2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride, (2R)- (9CI);1-Propanaminium, 2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride, (R)-;Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, acetate, (-)- (8CI);Acetyl L-carnitine hydrochloride;Acetylcarnitine chloride;Branigen;L-Acetylcarnitine chloride;Levacecarnine hydrochloride;Normobren;O-Acetylcarnitine hydrochloride;ST 200;Zibren;l-Acetylcarnitinehydrochloride;
O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
InChI:InChI=1/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
Relevant articles related to O-Acetyl-L-carnitine hydrochloride:
Article |
Source |
Enzyme-Catalyzed Synthesis of L-Acetylcarnitine and Citric Acid Using Acetyl Coenzyme A Recycling |
Patel, Smita S.,Conlon, Hugh D.,Walt, David R. , p. 2842 - 2844 (1986) |
A chloride process for the preparation of acetyl L-carnitine |
- Paragraph 0059; 0060; 0061; 0062, (2016/10/31) |
Acetyl L-carnitine hydrochloride preparation method |
- Paragraph 0017; 0018; 0019; 0020; 0021; 0022; 0023-0031, (2017/02/09) |
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