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CasNo： 489-32-7
MF： C33H40O15
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Icariin has been used as a test material to investigate its, in vitro effect in promoting mouse hair follicle growth, which is assessed by vibrissae hair follicle (VHF) organ-culture model.
3-O-(2′′′′,3′′′′,4′′′′-tri-O-acetyl-α-L-rhamnopyranosyl)-7-O-(2′′′,3′′′,4′′′,6′′′-tetra-O-acetyl-β-D-glucopyranosyl)icaritin
icariin
| Conditions | Yield |
|---|---|
|
With
ammonia;
In
methanol;
at 20 ℃;
for 3h;
|
94% |
C39H48O19
icariin
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
ethanol; water;
at 50 ℃;
for 0.333333h;
Temperature;
|
6 mg |
The CAS number of Icariin is 489-32-7.
More information of Icariin 489-32-7 are:
|
CAS Number |
489-32-7 |
|
Density |
1.55 g/cm3 |
|
Melting Point |
231-232 °C |
|
Boiling Point |
948.5 °C at 760 mmHg |
|
Flash Point |
300.9 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.679 |
|
HS CODE |
29389090 |
|
PSA |
238.20000 |
|
LogP |
0.06790 |
|
Pka |
5.90±0.40(Predicted) |
Synonyms for Icariin 489-32-7:4H-1-Benzopyran-4-one,3-[(6-deoxy-a-L-mannopyranosyl)oxy]-7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-(9CI);Icariin (8CI);Icariine;Icariln;Ieariline;Epimedium Extract powder;
The chemical formula of Icariin is C33H40O15 which containing 33 Carbon atoms,40 Hydrogen atoms and 15 Oxygen atoms,and the molecular weight of Icariin is 676.672.
Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.
InChI:InChI=1/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
Relevant articles related to Icariin:
|
Article |
Source |
|
Ep7GT, a glycosyltransferase with sugar donor flexibility from: Epimedium pseudowushanense, catalyzes the 7- O -glycosylation of baohuoside |
Feng, Keping,Chen, Ridao,Xie, Kebo,Chen, Dawei,Liu, Jimei,Du, Wenyu,Yang, Lin,Dai, Jungui supporting information, p. 8106 - 8114 (2019/09/19) |
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