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CasNo: 5080-50-2
MF: C9H17NO4.HCl
Appearance: Crystallline powder
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Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund''s adjuvant.
O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
The CAS number of O-Acetyl-L-carnitine hydrochloride is 5080-50-2.
More information of O-Acetyl-L-carnitine hydrochloride 5080-50-2 are:
CAS Number |
5080-50-2 |
Melting Point |
194 °C (dec.)(lit.) |
Refractive Index |
-28 ° (C=1, H2O) |
HS CODE |
29239000 |
PSA |
63.60000 |
LogP |
-2.89700 |
The chemical formula of O-Acetyl-L-carnitine hydrochloride is C9H17NO4.HCl which containing 9 Carbon atoms,18 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight, and the molecular weight of O-Acetyl-L-carnitine hydrochloride is 239.699
Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund''s adjuvant.
InChI:InChI=1/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
Relevant articles related to O-Acetyl-L-carnitine hydrochloride:
Article |
Source |
Enzyme-Catalyzed Synthesis of L-Acetylcarnitine and Citric Acid Using Acetyl Coenzyme A Recycling |
Patel, Smita S.,Conlon, Hugh D.,Walt, David R. , p. 2842 - 2844 (1986) |
Synthesis of carnitine benzyl esters as prodrugs |
Gong, Xiao-Wei,Li, Jin-Pei,Wu, Ji-Feng,Li, Xun,Zhai, Hai-Min,Feng, Bo,Xu, Wen-Fang,Tang, Wei experimental part, p. 327 - 330 (2009/05/30) |
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