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CasNo: 29908-03-0
MF: C15H22N6O5S
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white powder LOD 0.2%
L-methionine
ATP
S-Adenosyl-L-methionine
5'-Deoxy-5'-methylthioadenosine
Conditions | Yield |
---|---|
With
recombinant Methanocaldococcus jannaschii methionine adenosyltransferase; potassium chloride; magnesium chloride;
In
aq. buffer;
at 65 ℃;
for 4h;
pH=8;
Temperature;
Reagent/catalyst;
Enzymatic reaction;
|
1-methylhexahydropyrylium tetrafluoroborate
S-(5'-adenosyl)-L-homocysteine
S-Adenosyl-L-methionine
Conditions | Yield |
---|---|
1-methylhexahydropyrylium tetrafluoroborate; S-(5'-adenosyl)-L-homocysteine;
With
sulfuric acid; trifluoroacetic acid;
at 0 ℃;
In
dichloromethane; water;
Product distribution / selectivity;
|
The CAS number of S-Adenosyl-L-methionine is 29908-03-0.
More information of S-Adenosyl-L-methionine 29908-03-0 are:
CAS Number |
29908-03-0 |
Melting Point |
247-249oC |
HS CODE |
29349990 |
PSA |
547.02000 |
LogP |
-0.26280 |
Synonyms for S-Adenosyl-L-methionine 29908-03-0:SAMe (S-Adenosyl-L-Methionine butanedisulfonate);Adenosine,5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, hydroxide, inner salt,(3S)-;Adenosine, 5'-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-,hydroxide, inner salt (8CI);Methionine, S-adenosyl- (6CI);Active methionine;Ademetionine;AdoMet;Donamet;L-Methionine, S-adenosyl-;L-S-Adenosylmethionine;S Amet;SAMe;Adenosine,5'-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-, inner salt;
The chemical formula of S-Adenosyl-L-methionine is C15H22N6O5S which containing 15 Carbon atoms,22 Hydrogen atoms,6 Nitrogen atoms,5 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of S-Adenosyl-L-methionine is 398.443.
S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet) is a chemical that is found naturally in the body. SAMe is sold in the United States as a dietary supplement. S-Adenosyl-L-methionine was discovered in the early 1950s. It’s made in the body from methionine, an amino acid found in foods. It has been found to regulate key functions in living cells. Abnormal levels of S-Adenosyl-L-methionine in the body have been reported in liver diseases and depression. This prompted researchers to investigate whether S-Adenosyl-L-methionine might be helpful in treating these conditions. The idea that S-Adenosyl-L-methionine might be helpful for osteoarthritis came from studies of S-Adenosyl-L-methionine for depression. Some of the participants in the depression studies who also had osteoarthritis said their joint symptoms improved when they took S-Adenosyl-L-methionine.
InChI:InChI=1/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1
Relevant articles related to S-Adenosyl-L-methionine:
Article |
Source |
Mechanism of a Class C Radical S-Adenosyl- l -methionine Thiazole Methyl Transferase |
Zhang, Zhengan,Mahanta, Nilkamal,Hudson, Graham A.,Mitchell, Douglas A.,Van Der Donk, Wilfred A. , p. 18623 - 18631 (2017/12/26) |
Chemical Synthesis Of S-Adenosyl-L-Methionine With Enrichment Of (S,S)-Isomer |
- Page/Page column 4; 5, (2008/06/13) |
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