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CasNo: 57-83-0
MF: C21H30O2
Appearance: Crystalline powder
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Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.
Steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.Progesterone is a contaminant of emerging concern (CECs).
The CAS number of Progesterone is 57-83-0.
More information of Progesterone 57-83-0 are:
CAS Number |
57-83-0 |
Density |
1.08 g/cm3 |
Melting Point |
128-132 °C(lit.) |
Boiling Point |
447.2 °C at 760 mmHg |
Flash Point |
166.7 °C |
Vapor Pressure |
5.44E-10mmHg at 25°C |
Refractive Index |
182 ° (C=2, Dioxane) |
HS CODE |
29372390 |
PSA |
34.14000 |
LogP |
4.72350 |
The chemical formula of Progesterone is C21H30O2 which containing 21 Carbon atoms,30 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of Progesterone is 314.468
Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Δ4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.
InChI:InChI=1/C24H34O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h13-14,18-20H,6-12H2,1-5H3/t14-,18+,19-,20-,22+,23-,24-/m0/s1
Relevant articles related to Progesterone:
Article |
Source |
Regulation of steroidogenesis in the ovine corpus luteum |
Silavin,Moss,Niswender , p. 229 - 241 (1980) |
- |
Spielman,Meyer , p. 893 (1939) |
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