What is the Propionyl-L-carnitine hydrochloride?

Propionyl-L-carnitine hydrochloride is , while it's Molecular Formula is C10H20ClNO4. L-Propionyl carnitine has been shown to improve the heart''s mechanical recovery and other metabolic parameters after ischemia-reperfusion.

What is the CAS number for Propionyl-L-carnitine hydrochloride?

The CAS number of Propionyl-L-carnitine hydrochloride is 119793-66-7.

What is Propionyl-L-carnitine hydrochloride (119793-66-7) used for?

Propionyl-L-carnitine is a naturally occurring carnitine derivative formed by carnitine acetyltransferase during β-oxidation of uneven chain fatty acids. Propionyl-L-carnitine increases the basal release of prostaglandin E2 (PGE2; ) and 6-keto-prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils and increases the basal release of thromboxane B2 (TXB2; ) in non-contaminated cells. It reduces the production of reactive oxygen species (ROS) and decreases the expression of NADPH oxidase 2 (NOX2), NOX4, and ICAM-1 in human umbilical vein endothelial cells (HUVECs). It also increases the rate of revascularization and the hind limb vascular area in a rabbit model of hind limb ischemia when administered at a dose of 10 mg per animal. Propionyl-L-carnitine reduces mitochondrial dysfunction induced by ischemia, preventing mitochondrial calcium overload, and depletion of ATP tissue stores in a rabbit model of ischemia.InChI:InChI=1/C10H19NO4.ClH/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4;/h8H,5-7H2,1-4H3;1H/t8-;/m1./s1

What is the Propionyl-L-carnitine hydrochloride?

Propionyl-L-carnitine hydrochloride is , while it's Molecular Formula is C10H20ClNO4. L-Propionyl carnitine has been shown to improve the heart''s mechanical recovery and other metabolic parameters after ischemia-reperfusion.

What is the CAS number for Propionyl-L-carnitine hydrochloride?

The CAS number of Propionyl-L-carnitine hydrochloride is 119793-66-7.

What is Propionyl-L-carnitine hydrochloride (119793-66-7) used for?

Propionyl-L-carnitine is a naturally occurring carnitine derivative formed by carnitine acetyltransferase during β-oxidation of uneven chain fatty acids. Propionyl-L-carnitine increases the basal release of prostaglandin E2 (PGE2; ) and 6-keto-prostaglandin F1α in carrageenan-stimulated isolated rat peritoneal cells contaminated with neutrophils and increases the basal release of thromboxane B2 (TXB2; ) in non-contaminated cells. It reduces the production of reactive oxygen species (ROS) and decreases the expression of NADPH oxidase 2 (NOX2), NOX4, and ICAM-1 in human umbilical vein endothelial cells (HUVECs). It also increases the rate of revascularization and the hind limb vascular area in a rabbit model of hind limb ischemia when administered at a dose of 10 mg per animal. Propionyl-L-carnitine reduces mitochondrial dysfunction induced by ischemia, preventing mitochondrial calcium overload, and depletion of ATP tissue stores in a rabbit model of ischemia.InChI:InChI=1/C10H19NO4.ClH/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4;/h8H,5-7H2,1-4H3;1H/t8-;/m1./s1

Propionyl L-Carnitine HCl

Basic information

Product Name:Propionyl L-Carnitine HCl
CasNo.:119793-66-7
MF:C₁₀H₂₀ClNO₄
MW:253.726

Physical and Chemical Properties

Purity:99%
Boiling Point:165-167°C
Packing:
Throughput:

Inquiry

Product Details

CasNo： 119793-66-7

MF： C₁₀H₂₀ClNO₄

Reliable factory customized supply Propionyl L-Carnitine HCl 119793-66-7

Molecular Formula:C10H20ClNO4
Molecular Weight:253.726
Melting Point:165-167°C
PSA：63.60000
LogP:-2.50690

Propionyl-L-carnitine hydrochloride(Cas 119793-66-7) Usage

Brand name

Dromos (Biosint S.p.A.).

InChI:InChI=1/C10H19NO4.ClH/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4;/h8H,5-7H2,1-4H3;1H/t8-;/m1./s1

119793-66-7 Relevant articles

Synthesis of carnitine benzyl esters as prodrugs

Gong, Xiao-Wei,Li, Jin-Pei,Wu, Ji-Feng,Li, Xun,Zhai, Hai-Min,Feng, Bo,Xu, Wen-Fang,Tang, Wei

experimental part, p. 327 - 330 (2009/05/30)

The introduction of C-2 acyl groups and ...

119793-66-7 Process route

: 79-03-8
propionyl chloride

: 6645-46-1
L-carnitine chloride

: 119793-66-7
(R)-3-carboxy-N,N,N-trimethyl-2-(propionyloxy)propan-1-ammonium chloride

Conditions

Conditions	Yield
With trifluoroacetic acid; at 40 - 50 ℃; for 20h;

119793-66-7 Upstream products

79-03-8
propionyl chloride
6645-46-1
L-carnitine chloride

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