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CasNo： 1098-97-1
MF： C16H20N2O4S2
Appearance： COA
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World Health Organization (WHO) |
Pyritinol, which is claimed to promote the uptake of glucose in the brain, is used in the treatment of cerebrovascular disorders. However, WHO is not aware of controlled experimental data to show that it has any therapeutic effect. |
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Brand name |
Biontabol;Bonifwn;Cefalogen;Cerebrotrofina;Cervitalin;Divalvon-d;Enbol;Encefort;Encerbrovit;Encerebron;Fulneurina;Geribolina;Gerontabol comp.;Juniormen;Leonar;Logos;Maind;Musa;Neuroxin;Piriditol;Piririomin;Piritinol;Piritiomin;Plenumil;Sawaxin;Scintidin;Tibased;Tomevit;Tonobrein;Tonomentis. |
InChI:InChI=1/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3
The invention relates to the technical f...
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pyrithioxin dihydrochloride
Pyritinol
| Conditions | Yield |
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With
sodium carbonate;
In
water;
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70% |
Pyritinol
| Conditions | Yield |
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3-Hydroxy-2-methyl-5-chlormethyl-4-hydroxymethyl-pyridin, Na2S*9H2O, Schwefel, 60grad, 1h;
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entspr. Xanthate 1;
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5-Pyridoxthiol, NH4OH;
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(yield)92percent;
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3-Hydroxy-2-methyl-5-brommethyl-4-hydroxymethyl-pyridin, Na2S*9H2O, Schwefel;
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2-Methyl-3-hydroxy-4-hydroxymethyl-5-chlormethylpyridin*HCl (V), 1. Na2S2/W., 2. 10percentig. wss.HCl;
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Pyridoxin-hydrochlorid, 1.) CH2Cl2/SOCl2, 9 Std., 50grad --> 2-Me-3-OH-4,5-CH2Cl-Pyridin, 2.) Wasser, 60-65grad, 1.5 Std., 3.) Na2S2, 20grad, 4.) 60grad, 2 Std.;
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entspr. 3-Thiocyanatmethyl-pyridin, NH3/H2S;
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5-Brommethyl-3-hydroxy-4-hydroxymethyl-2-methyl-pyridin (VIII)*HBr, Na2S2/W.;
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entspr. Thiosulfonat II, Jod;
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entspr. Thiosulfat, entspr. Mercaptan;
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1,3-Dioxo-7-azanaphthalin, Thioharnstoff;
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Na-4-Hydroxymethyl-5-hydroxy-6-methyl-3-pyridyl-methylthiosulfat, Na2S;
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Verb. V, - Hydrolyse;
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Bis<(4-methoxymethyl-5-hydroxy-6-methyl-3-pyridyl)-methyl>disulfid V, konz.HCl;
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S-(2-Methyl-3-hydroxy-4-hydroxymethyl-pyridin-5-ylmethyl)isothioharnstoff*2HCl, H2O2-NaOH;
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Pyridin II, Na2S, S;
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Pyridin III, Na2S, S;
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pyrithioxin dihydrochloride
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