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CasNo： 102518-79-6
MF： C15H18N2O
Appearance： white to slight white crystaline powder
High Quality Chinese Manufacturer supply 102518-79-6 Huperzine A1% We supply high quality (-)-Huperzine A (CAS 102518-79-6), in stock, factory directly supply to clients, lower prices, more competitiveness.
(-)-Huperzine A is white to slight white crystaline powder, while it's Molecular Formula is C15H18N2O. Huperzine A is a potential therapeutic agent for Alzheimer disease that reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cere.In China, it is approved for use in the treatment of Alzheimer’s disease (AD). Huperzine A was classified as a dietary supplement by the FDA in 1997. As a nutraceutical, it is available in American health food stores or via the Internet, labeled as a memory aid.
The CAS number of (-)-Huperzine A is 102518-79-6.
More information of (-)-Huperzine A 102518-79-6 are:
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Synonyms |
Selagine;5,9-Methanocycloocta[b]pyridin-2(1H)-one,5- amino-11-ethylidene-5,6,9,10-tetrahydro-7- methyl-,(5R,9R,11E)-;Huperzine;5,9-Methanocycloocta(b)pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R-(5-alpha,9-beta,11E))-;5,9-Methanocycloocta(b)pyridin-2(1H)-one, 5-amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R,9R,11E)-;5,9-Methanocycloocta[b]pyridine-2(1H)-one,5-amino-11-ethylid-Ene-5,6,9,10-tetrahydro-7-methyl-,[5R-(5a,9,11E)]-;Huperzine-A;Huperzine Serrate Extract ,Huperzine A 98%;Serrate Clubmoss extract;Verticine;Chinese Traditional Natural Health Care Plant of Da zao/Chinese Date Extract; |
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CAS Number |
102518-79-6 |
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Molecular Formula |
C15H18N2O |
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Molecular Weight |
242.321 |
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Density |
1.2 g/cm3 |
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Melting Point |
211-216 °C |
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Boiling Point |
505 °C at 760 mmHg |
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Flash Point |
259.2 °C |
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HS CODE |
29339900 |
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PSA |
58.88000 |
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LogP |
2.69780 |
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Pka |
12.25±0.60(Predicted) |
Huperzine A is obtained from Huperzia serrata, which is the perennial fern. It shows activities in antipyretic, hemostasis, and dehumidification and is used for the treatment in folk of pneumonia, lung abscess, hematemesis, hematochezia, traumatic injury, etc.
InChI:InChI=1/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+/t10-,15+/m0/s1
Articles related to (-)-Huperzine A:
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Article |
Source |
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A total synthesis of (+-)-huperzine A |
Qian,Ji , p. 2089 - 2090 (1989) |
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A Palladium-Catalyzed Route to Huperzine A and Its Analogues and Their Anticholinesterase Activity |
Campiani, Giuseppe,Sun, Li-Qiang,Kozikowski, Alan P.,Aagaard, Patricia,McKinney, Michael , p. 7660 - 7669 (1993) |
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