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CasNo： 633-65-8
MF： C20H18NO4.Cl
Appearance： yellow crystalline powder
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An ingredient in some commercial eyewash products.
![2-(6-(2-(2-(1,3-dioxolan-2-yl)-3,4-dimethoxyphenyl)acetyl)benzo[d][1,3]dioxol-5yl)ethyl pivalate](/upload/2025/12/6182edfe-7489-4951-a482-8875eaf58022.png)
2-(6-(2-(2-(1,3-dioxolan-2-yl)-3,4-dimethoxyphenyl)acetyl)benzo[d][1,3]dioxol-5yl)ethyl pivalate
berberine chloride
| Conditions | Yield |
|---|---|
|
With
ammonium chloride;
In
ethanol; water;
at 110 ℃;
for 24h;
Concentration;
Solvent;
|
89.4% |
|
With
ammonium chloride;
In
ethanol; water;
at 90 - 110 ℃;
for 56h;
|
82% |
C20H17NO4
berberine chloride
| Conditions | Yield |
|---|---|
|
With
ammonium chloride;
In
water;
at 150 ℃;
for 40h;
Inert atmosphere;
Sealed tube;
|
37% |
The CAS number of Berberine hydrochloride is 633-65-8.
More information of Berberine hydrochloride 633-65-8 are:
|
CAS Number |
633-65-8 |
|
Density |
1.654g/cm3 |
|
Melting Point |
204-206 °C (dec.) |
|
HS CODE |
29349990 |
|
PSA |
40.80000 |
|
LogP |
0.10030 |
Synonyms for Berberine hydrochloride 633-65-8:NSC 646666;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride (9CI);Berberine, chloride (6CI,7CI);Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride (8CI);Berberinium chloride;
The chemical formula of Berberine hydrochloride is C20H18NO4.Cl which containing 20 Carbon atoms,18 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight of Berberine hydrochloride is 371.82.
Berberine hydrochloride is an isoquinoline alkaloid derived from various plant sources, such as barberry, goldenseal, and Oregon grape. It exhibits a wide range of pharmacological properties, including antiarrhythmic, alpha2 agonist, anticonvulsant, anti-inflammatory, antibacterial, antifungal, antitrypanosomal, antineoplastic, and immunostimulant activities. Berberine hydrochloride has gained attention for its potential chemopreventive properties and its ability to inhibit the enzyme cyclooxygenase-2 (COX-2) and Activator Protein 1 (AP-1), which play critical roles in inflammation and carcinogenesis.
InChI:InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;
Relevant articles related to Berberine hydrochloride:
|
Article |
Source |
|
The total synthesis of berberine and selected analogues, and their evaluation as amyloid beta aggregation inhibitors |
Tajiri, Misato,Yamada, Ryo,Hotsumi, Mayumi,Makabe, Koki,Konno, Hiroyuki , (2021/02/26) |
|
A synthetic preparation method for small carbags hydrochloric acid |
- Paragraph 0276-0286, (2021/12/08) |
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