What is the HYDROQUININE?

HYDROQUININE is , while it's Molecular Formula is C20H26N2O2. (-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.

What is the CAS number for HYDROQUININE?

The CAS number of HYDROQUININE is 522-66-7.

What is HYDROQUININE (522-66-7) used for?

HYDROQUININE, also known as (-)-Dihydroquinine, is a dihydro derivative of Quinine. It is a solid substance with various medicinal properties, including antipyretic (fever-reducing), antimalarial, analgesic (pain-killing), and anti-inflammatory characteristics. These properties make it a versatile compound for pharmaceutical applications.InChI:InChI=1/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m1/s1

What is the HYDROQUININE?

HYDROQUININE is , while it's Molecular Formula is C20H26N2O2. (-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.

What is the CAS number for HYDROQUININE?

The CAS number of HYDROQUININE is 522-66-7.

What is HYDROQUININE (522-66-7) used for?

HYDROQUININE, also known as (-)-Dihydroquinine, is a dihydro derivative of Quinine. It is a solid substance with various medicinal properties, including antipyretic (fever-reducing), antimalarial, analgesic (pain-killing), and anti-inflammatory characteristics. These properties make it a versatile compound for pharmaceutical applications.InChI:InChI=1/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m1/s1

Dihydroberberine

Basic information

Product Name:Dihydroberberine
CasNo.:522-66-7
MF:C₂₀H₂₆N₂O₂
MW:326.439

Physical and Chemical Properties

Purity:99%
Boiling Point:168-176 °C
Packing:
Throughput:

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Product Details

CasNo： 522-66-7

MF： C₂₀H₂₆N₂O₂

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Molecular Formula:C20H26N2O2
Molecular Weight:326.439
Vapor Pressure:9.45E-11mmHg at 25°C
Melting Point:168-176 °C
Refractive Index:1.626
Boiling Point:498.4 °C at 760 mmHg
PKA:5.33(at 25℃)
Flash Point:255.2 °C
PSA：45.59000
Density:1.2 g/cm³
LogP:3.33510

HYDROQUININE(Cas 522-66-7) Usage

Purification Methods

Hydroquinine [522-66-7] M 326.4, m 168-171o, 171.5o, [ ] D-143o (c 1.087, EtOH), 5.33 and 8.87. Recrystallise hydroquinine from EtOH, Et2O or *C6H6. [Rabe & Schultz Chem Ber 66 120 1933, Beilstein 23 III/IV 3193, 23/13 V 340.]

InChI:InChI=1/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m1/s1

522-66-7 Relevant articles

Convenient synthesis of cobalt nanoparticles for the hydrogenation of quinolines in water

Beller, Matthias,Dorcet, Vincent,Fischmeister, Cedric,Hervochon, Julien,Junge, Kathrin

, p. 4820 - 4826 (2020/08/14)

Easily accessible cobalt nanoparticles a...

Synthesis method of hydroquinine(anthraquinone-1,4-diyl)diether

-

Paragraph 0072; 0073; 0074; 0075; 0076, (2020/10/21)

The invention discloses a synthetic meth...

A Cinchona Alkaloid Antibiotic That Appears to Target ATP Synthase in Streptococcus pneumoniae

Wang, Xu,Zeng, Yuna,Sheng, Li,Larson, Peter,Liu, Xue,Zou, Xiaowen,Wang, Shufang,Guo, Kaijing,Ma, Chen,Zhang, Gang,Cui, Huaqing,Ferguson, David M.,Li, Yan,Zhang, Jingren,Aldrich, Courtney C.

, p. 2305 - 2332 (2019/04/25)

Optochin, a cinchona alkaloid derivative...

Expansion of the aromatic part of Cinchona alkaloids. Annulation of quinolines with phenoxazine motifs

W?sińska-Ka?wa, Ma?gorzata,Giurg, Miros?aw,Boratyński, Przemys?aw J.,Skar?ewski, Jacek

, p. 308 - 315 (2017/12/08)

An oxidative cross-coupling strategy for...

522-66-7 Process route

: 130-95-0
Quinine

: 522-66-7
dihydroquinine

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen; In methanol; for 3h; under 2280.15 Torr; Inert atmosphere;	100%
With palladium on carbon; hydrogen; for 72h;	97%
With sodium tetrahydroborate; hydrogen; cobalt(II) chloride; In water; at 150 ℃; for 17h; under 22502.3 Torr; chemoselective reaction; Green chemistry;	95%
With hydrogenchloride; platinum chlorides; Hydrogenation;
With palladium on activated charcoal; hydrogen;
With formic acid; Pd/C; triethylamine; In ethanol; at 30 ℃; for 1.5h;
With 3-methyl-1-butyl acetate; palladium; at 50 - 60 ℃; under 1520 - 3040 Torr; Reagens 4: Eisessig;
With 3-methyl-1-butyl acetate; platinum; at 50 - 60 ℃; under 1520 - 3040 Torr; Reagens 4: Eisessig;
With 5%-palladium/activated carbon; hydrogen; In methanol; at 35 ℃; for 5h; under 3800.26 Torr; Solvent; Reagent/catalyst; Large scale;	25.2 kg

: 241147-96-6
2-(4-(tert-butyl)phenyl)benzo[d][1,3,2]dioxaborole

: 130-95-0
Quinine

: 98-54-4
para-tert-butylphenol

: 522-66-7
dihydroquinine

Conditions

Conditions	Yield
With oxygen; hydrazine hydrate; In acetonitrile; at 32 ℃; for 4h; under 760.051 Torr; Schlenk technique;	87% 57%

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